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MÜLLER, JOHANNES & THEODOR SCHWANN. - THE DISCOVERY OF PEPSIN, THE FIRST KNOWN ANIMAL ENZYME & THE "FIBRES OF REMAK

Versuche über die künstliche Verdauung des geronnenen Eiweisses (Müller & Schwann) (+) Ueber das Wesen des Verdauungsprocesses (Schwann). 2 paers.

lyn45406

Berlin, G. Eichler, 1836. In "Archiv für Anatomie, Physiologie und Wissenschaftliches Medicin Herausgegeben von Johannes Müller". Jahrgang 1836. Pp. 66-89 a. pp. 90-139. The entire volume offered in its 6 parts (in 5), all 5 issues uncut with orig. printed warppers. (2),CCXXIV,390 pp. and 15 engraved plates. The 2 first issues with a faint dampstain to lower part of leaves and plates. ¶ First appearance of an importent paper in the history of biology, in which Schwann describes his discovery and isolation of pepsin, the substance in the stomach that aids digestion of eggwhite. It is the FIRST KNOWN ANIMAL ENZYME. The paper appeared at the same time in "Annalen der Physik und Chemie. Hrsg. von J.C. Poggendorff".

Theodor Schwann (1810-1882) was a great German physiologist, pathologist, and experimenter. One of the founders of the cell doctrine and of the idea of the living nature of yeast. Born at Neuss, near Düsseldorff. A catholic, educated in the Jesuit Gymnasium in Cologne. Intended for the church but took to medicine. He was a pupil of Johannes Müller and a collegueand lifelong friend of J. Henle, the anatomist. In Berlin Schwann was Johannes Müller's assistent for five years, and it was then that he discovered pepsin in 1836 (the paper offered).

Parkinson "Breakthroughs" 1836 B. - Garrison & Morton no. 991.

The first paper offered, written together with Johannes Müller records the preliminary investigaions leading to the discovery of Pepsin. - Garrison & Morton no. 990.

The volume also contains another famous paper by ROBERT REMAK "Vorläufige Mittheilung microscopischer Beobachtungen über den innern Bau der Cerebrospinalnerven und über die Entwicklung ihrer Formenelemente. (Hierzu Tafel IV). Pp. 145-161. This paper contains the first announcement of his DISCOVERY OF "FIBRES OF REMAK", the non-medullated nerve-fibres. (Garrison & Morton no. 1260.

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