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CHAIN, ERNST., HOWARD WALTER FLOREY, M.A. JENNINGS (ET AL).

Penicillin as a Chemotherapeutic Agent. + Further Observations on Penicillin.

lyn45509

London, Hazell, Watson & Viney, 1940-41. Extracted from The Lancet, 24 August 1940 p.226-28, 16 August 1941 p.177-88. Recent paper wrappers. Due to a piece of tape removed from p. 225 there is a loss of a few letters on p. 226. Remains of the tape seen on p. 226. ¶ First editions. Alexander Fleming's discovery of penicillin "might well have become an obscure scientific curiosity but for the work of Chain and Florey" (Printing and the Mind of Man). "Penicillin as a Chemotherapeutic Agent" reported their first clinical tests of penicillin, on mice; "Further Observations on Penicillin" detailed the first tests on humans, and suggested methods of large-scale production of penicillin. Chain and Florey shared the 1945 Nobel Prize in Medicine with Fleming "for the discovery of penicillin and its curative effect in various infectious diseases". PMM 420(b), Norman 437, GM 1933.

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